HELPING THE OTHERS REALIZE THE ADVANTAGES OF BLOCK PAIN RECEPTORS WITH PROLEVIATE

The activation of CB1 and CB2 inhibits the development of intracellular cAMP, as a result resulting in an amazing reduction from the excitatory result within the neurons [88,89]. Moreover, the activation of CB2 can further avoid the mast cell degranulation and the release of professional-inflammatory mediators, earning the reduction in pain feeling